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— Research Streams

Research organized by theme and method.

Substantive streams focus on specific policy domains; methodological streams represent analytical approaches that cut across applications.

Substantive

3 streams
Cancer Early Detection & Prevention 20

Microsimulation and cost-effectiveness analysis to improve cancer screening, reduce disparities, and inform clinical guidelines.

  • 2026 Cancer Diagnostic Delay Rates Associated With a Population-Based Screening Trial Evaluating a Cell-Free DNA Multicancer Early Detection Test
  • 2026 CRC-SPIN Version 3.0: An Updated Policy Model for Colorectal Cancer Screening That Includes the Serrated Pathway
Pandemic Preparedness & Response 18

Decision support tools and surveillance systems for policymakers responding to infectious disease threats.

  • 2026 A Framework for Evaluating Implementation, Impact, and Cost-Effectiveness of Wastewater and Environmental Surveillance
  • 2026 Uncertainty Aware Decision Support with Computationally Expensive Simulation Models: A Case Study of HIV Intervention Scenarios
Equity & Society 12

How social determinants and structural factors shape health outcomes, and which policies promote equity.

  • 2025 Cost-Effectiveness of Noninvasive Colorectal Cancer Screening in Community Clinics
  • 2025 Modeled Cost-Effectiveness of a Rideshare Program to Facilitate Colonoscopy Completion

Methodological

4 streams
Modeling & Simulation 39

Microsimulation, agent-based, and epidemic models for understanding complex systems and evaluating policy interventions.

  • 2026 CRC-SPIN Version 3.0: An Updated Policy Model for Colorectal Cancer Screening That Includes the Serrated Pathway
  • 2026 Uncertainty Aware Decision Support with Computationally Expensive Simulation Models: A Case Study of HIV Intervention Scenarios
Robust Decision Making 7

Frameworks for making decisions under deep uncertainty — finding strategies robust across many plausible futures.

  • 2025 Incorporating social determinants of health into agent-based models of HIV transmission: methodological challenges and future directions
  • 2025 Stress-testing US colorectal cancer screening guidelines: Decennial colonoscopy from age 45 is robust to natural history uncertainty and colonoscopy sensitivity assumptions
Causal Inference 4

Evaluating methods for estimating policy effects from observational data.

  • 2026 Cancer Diagnostic Delay Rates Associated With a Population-Based Screening Trial Evaluating a Cell-Free DNA Multicancer Early Detection Test
  • 2026 Assessing Bias and Precision in State Policy Evaluations: A Comparative Analysis of Time-Varying Estimators Using Policy Simulations
Tools & Packages 11

Open-source R packages and software supporting reproducible research and applied methods.

  • 2026 Simpler Is Better For Autograders: Achieving Cost-Effective LLM Evaluations for Open-Ended Tasks
  • 2026 heormodel: Python framework for Health Economics and Outcomes Research